WebNM_021117.5(CRY2):c.161A>G (p.Tyr54Cys) AND Inborn genetic diseases Clinical significance: Uncertain significance (Last evaluated: Oct 5, 2024) Review status: 1 star out of maximum of 4 stars WebCryptochromes (cry1 and cry2) are blue light photoreceptors that mediate various light-induced responses in plants and animals. It has been demonstrated that Arabidopsis cry1 and cry2 function through negatively regulating CONSTITUTIVE PHOTOMORPHOGENESIS 1 (COP1), a repressor of photomorphogenesis ( Cashmore, …
Cryptochrome - Wikipedia
WebMay 11, 2024 · Here we show that photoexcited Arabidopsis cryptochrome 2 (CRY2) is phosphorylated in vivo on as many as 24 different residues, including 7 major phosphoserines. We demonstrate that four closely related Photoregulatory Protein Kinases (previously referred to as MUT9-like kinases) interact with and phosphorylate … WebDec 10, 2024 · Both CRY1 and CRY2 are structurally similar, containing a highly conserved N-terminal domain, the photolyase homology region (PHR), which evolved from DNA photolyases and a C-terminal domain known as cryptochrome carboxyl terminus (CCT) ( … easter65
Molecular basis for blue light-dependent phosphorylation of
WebJun 12, 2024 · Here, we report crystal structures of CRY2N (CRY2 PHR domain) and the BIC2-CRY2N complex with resolutions of 2.7 and 2.5 Å, respectively. In the BIC2-CRY2N complex, BIC2 exhibits an extremely extended structure that sinuously winds around CRY2N. In this way, BIC2 not only restrains the transfer of electrons and protons from … WebMouse Cry2 Protein (raised in Insect Cells) purified by multi-step, protein-specific process to ensure crystallization grade. State-of-the-art algorithm used for plasmid design (Gene synthesis). This protein is a made to order protein and … WebSep 18, 2015 · Based on the light dependent binding of cryptochrome 2 and a cryptochrome interacting bHLH protein, ... Among molecular partners of this type, the blue light dependent binding of cryptochrome 2 (CRY2) to its partner cryptochrome interacting protein (CIB), has been the most studied as this system offers rapid on- and off-kinetics … cub scout pack number patch