WebbLyophilized aliquots of filter extracts were analyzed for 3-hydroxy fatty acids ( 3-OHFAs) as a marker of LPS using gas chromatography-mass spectrometry. There were significant … Webbof two exemplary, long-chain 3-OHFAs, 3-hydroxystearate and 3-hydroxypalmitate. Using different approaches, namely purified P450 reconstitution, immunochemistry, and en-zyme kinetics, we found that a member of the CYP4F gene subfamily, CYP4F11, was the predominant catalyst of this fatty acid oxidation reaction in human liver. Fig. 1.

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Lactic acid bacteria producing antifungal hydroxyl-fatty acid

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